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Index > Protein center > COL15A1(Gene name) > Human
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  • COL15A1 (Gene name),
  • Collagen alpha-1(XV) chain (Protein name ),  COFA1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    COL15A1;
    Protein name:
    Collagen alpha-1(XV) chain;
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Trimer; disulfide-linked.
    Function:
    Endostatin potently inhibits angiogenesis.
    Subcellular Location:
    Secreted extracellular space extracellular matrix
    Protein Attributes:
    Sequence length:
    1388
    Sequence:
    50:
    MAPRRNNGQC | WCLLMLLSVS | TPLPAVTQTR | GATETASQGH | LDLTQLIGVP | 
    100:
    LPSSVSFVTG | YGGFPAYSFG | PGANVGRPAR | TLIPSTFFRD | FAISVVVKPS | 
    150:
    STRGGVLFAI | TDAFQKVIYL | GLRLSGVEDG | HQRIILYYTE | PGSHVSQEAA | 
    200:
    AFSVPVMTHR | WNRFAMIVQG | EEVTLLVNCE | EHSRIPFQRS | SQALAFESSA | 
    250:
    GIFMGNAGAT | GLERFTGSLQ | QLTVHPDPRT | PEELCDPEES | SASGETSGLQ | 
    300:
    EADGVAEILE | AVTYTQASPK | EAKVEPINTP | PTPSSPFEDM | ELSGEPVPEG | 
    350:
    TLETTNMSII | QHSSPKQGSG | EILNDTLEGV | HSVDGDPITD | SGSGAGAFLD | 
    400:
    IAEEKNLAAT | AAGLAEVPIS | TAGEAEASSV | PTGGPTLSMS | TENPEEGVTP | 
    450:
    GPDNEERLAA | TAAGEAEALA | SMPGEVEASG | VAPGELDLSM | SAQSLGEEAT | 
    500:
    VGPSSEDSLT | TAAAATEVSL | STFEDEEASG | VPTDGLAPLT | ATMAPERAVT | 
    550:
    SGPGDEEDLA | AATTEEPLIT | AGGEESGSPP | PDGPPLPLPT | VAPERWITPA | 
    600:
    QREHVGMKGQ | AGPKGEKGDA | GEELPGPPEP | SGPVGPTAGA | EAEGSGLGWG | 
    650:
    SDVGSGSGDL | VGSEQLLRGP | PGPPGPPGLP | GIPGKPGTDV | FMGPPGSPGE | 
    700:
    DGPAGEPGPP | GPEGQPGVDG | ATGLPGMKGE | KGARGPNGSV | GEKGDPGNRG | 
    750:
    LPGPPGKKGQ | AGPPGVMGPP | GPPGPPGPPG | PGCTMGLGFE | DTEGSGSTQL | 
    800:
    LNEPKLSRPT | AAIGLKGEKG | DRGPKGERGM | DGASIVGPPG | PRGPPGHIKV | 
    850:
    LSNSLINITH | GFMNFSDIPE | LVGPPGPDGL | PGLPGFPGPR | GPKGDTGLPG | 
    900:
    FPGLKGEQGE | KGEPGAILTE | DIPLERLMGK | KGEPGMHGAP | GPMGPKGPPG | 
    950:
    HKGEFGLPGR | PGRPGLNGLK | GTKGDPGVIM | QGPPGLPGPP | GPPGPPGAVI | 
    1000:
    NIKGAIFPIP | VRPHCKMPVD | TAHPGSPELI | TFHGVKGEKG | SWGLPGSKGE | 
    1050:
    KGDQGAQGPP | GPPLDLAYLR | HFLNNLKGEN | GDKGFKGEKG | EKGDINGSFL | 
    1100:
    MSGPPGLPGN | PGPAGQKGET | VVGPQGPPGA | PGLPGPPGFG | RPGDPGPPGP | 
    1150:
    PGPPGPPAIL | GAAVALPGPP | GPPGQPGLPG | SRNLVTAFSN | MDDMLQKAHL | 
    1200:
    VIEGTFIYLR | DSTEFFIRVR | DGWKKLQLGE | LIPIPADSPP | PPALSSNPHQ | 
    1250:
    LLPPPNPISS | ANYEKPALHL | AALNMPFSGD | IRADFQCFKQ | ARAAGLLSTY | 
    1300:
    RAFLSSHLQD | LSTIVRKAER | YSLPIVNLKG | QVLFNNWDSI | FSGHGGQFNM | 
    1350:
    HIPIYSFDGR | DIMTDPSWPQ | KVIWHGSSPH | GVRLVDNYCE | AWRTADTAVT | 
    1388:
    GLASPLSTGK | ILDQKAYSCA | NRLIVLCIEN | SFMTDARK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    Pfam:
    KEGG:
    SMR:
    MIM:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Collagen alpha-1(XV) chain
    Cat.:
    E0542h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Collagen alpha-1(XV) chain
    Cat.:
    E0542m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Collagen alpha-1(XV) chain
    Cat.:
    U0542m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Collagen alpha-1(XV) chain
    Cat.:
    U0542h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Collagen alpha-1(XV) chain
    Cat.:
    P0542Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Collagen alpha-1(XV) chain
    Cat.:
    P0542Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Collagen alpha-1(XV) chain
    Monoclonal Antibody for Human Collagen alpha-1(XV) chain
    Protein for Human Collagen alpha-1(XV) chain
    Protein for Human Collagen alpha-1(XV) chain

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Linearity
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Primary structure of the alpha 1 chain of human type XV collagen and exon-intron organization in the 3' region of the corresponding gene."
      Kivirikko S. , Heinamaki P. , Rehn M.V. , Honkanen N. , Myers J.C. , Pihlajaniemi T.
      J. Biol. Chem.269:4773-4779(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]
      tissue: Umbilical cord.
    2. 2.
      "Complete exon-intron organization of the human gene for the alpha1 chain of type XV collagen (COL15A1) and comparison with the homologous COL18A1 gene."
      Haegg P.M. , Muona A. , Lietard J. , Kivirikko S. , Pihlajaniemi T.
      J. Biol. Chem.273:17824-17831(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    3. 3.
      "DNA sequence and analysis of human chromosome 9."
      Humphray S.J. , Oliver K. , Hunt A.R. , Plumb R.W. , Loveland J.E. , Howe K.L. , Andrews T.D. , Searle S. , Hunt S.E. , Scott C.E. , Jones M.C. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Ashwell R.I.S. , Babbage A.K. , Babbage S. , Bagguley C.L. , more...
      Nature429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "The human alpha 1(XV) collagen chain contains a large amino-terminal non-triple helical domain with a tandem repeat structure and homology to alpha 1(XVIII) collagen."
      Muragaki Y. , Abe N. , Ninomiya Y. , Olsen B.R. , Ooshima A.
      J. Biol. Chem.269:4042-4046(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-569;VARIANT VAL-204
      tissue: Placenta.
    5. 5.
      "Identification of a previously unknown human collagen chain, alpha 1(XV), characterized by extensive interruptions in the triple-helical region."
      Myers J.C. , Kivirikko S. , Gordon M.K. , Dion A.S. , Pihlajaniemi T.
      Proc. Natl. Acad. Sci. U.S.A.89:10144-10148(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 544-1252
    6. 6.
      "Chromosomal assignment of a gene encoding a new collagen type (COL15A1) to 9q21 --> q22."
      Huebner K. , Cannizzaro L.A. , Jabs E.W. , Kivirikko S. , Manzone H. , Pihlajaniemi T. , Myers J.C.
      Genomics14:220-224(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1105-1145;CHROMOSOMAL LOCATION
      tissue: Placenta.
    7. 7.
      "Identification and characterization of novel endogenous proteolytic forms of the human angiogenesis inhibitors restin and endostatin."
      John H. , Radtke K. , Staendker L. , Forssmann W.G.
      Biochim. Biophys. Acta1747:161-170(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 1198-1210; 1207-1219; 1213-1225 AND 1221-1233;IDENTIFICATION OF RESTIN-RELATED PEPTIDES;DISULFIDE BOND
    8. 8.
      "Antiangiogenic activity of restin, NC10 domain of human collagen XV: comparison to endostatin."
      Ramchandran R. , Dhanabal M. , Volk R. , Waterman M.J.F. , Segal M. , Lu H. , Knebelmann B. , Sukhatme V.P.
      Biochem. Biophys. Res. Commun.255:735-739(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    9. 9.
      "Basement membrane zone type XV collagen is a disulfide-bonded chondroitin sulfate proteoglycan in human tissues and cultured cells."
      Li D. , Clark C.C. , Myers J.C.
      J. Biol. Chem.275:22339-22347(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION;STRUCTURE OF CARBOHYDRATES;INTERCHAIN DISULFIDE BONDS
    10. 10.
      "Human urinary glycoproteomics; attachment site specific analysis of N-and O-linked glycosylations by CID and ECD."
      Halim A. , Nilsson J. , Ruetschi U. , Hesse C. , Larson G.
      Mol. Cell. Proteomics0:0-0(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT THR-265;STRUCTURE OF CARBOHYDRATES;IDENTIFICATION BY MASS SPECTROMETRY
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